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KMID : 1007420180160010038
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Mood and Emotion
2018 Volume.16 No. 1 p.38 ~ p.43
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Relationship between Suicidal Ideation and Plasma C-Reactive Protein Level in General Population : The Korean National Health and Nutrition Examination Survey
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Lee Jung-An
Park Seon-Cheol
Kim Gyung-Mee
Lee Bong-Ju
Park Sung-Woo
Seo Mi-Kyoung
Lee Jung-Goo
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Abstract
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Objectives : The purpose of this study is to inquire into the relationship between the association of suicidal ideation and the plasma C-reactive protein level in the general population.
Methods : This study selected a total of 5,090 subjects who have responded to the survey item on suicidal ideation status, and received the plasma C-reactive protein test, as a research subject using the 2015 data of the National Health and Nutrition Survey. This study conducted a covariance analysis by correcting a potential influence of demographic and hematological factors. Besides, this study intended to define the cut-off value of the optimum plasma C-reactive protein level, which once identified can distinguish between a subject with and without suicidal ideation using the model of the decision tree.
Results : The Plasma C-reactive protein level of a subject having suicidal ideation was noted as being significantly higher than the one having no suicidal ideation in the covariance analysis (p=0.046). In addition, the proper cut-off value of the plasma C-reactive protein level between the subjects with and without suicidal ideation was found to be 1.30 mg/L (p=0.003).
Conclusion : It is noted that the high plasma C-reactive protein level showed a significant correlation with individuals with noted suicidal ideation. In addition, this study has significance in that it presented that the plasma C-reactive protein concentration has the possibility as an accurate and significant marker of suicidal ideation in the general population.
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KEYWORD
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C-reactive protein (CRP), Decision tree, General population, Plasma, Suicidal ideation
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